Integra^® Wound Matrix

INTEGRA™ Wound Matrix is an advanced wound care device comprised of a porous matrix of cross-linked bovine tendon collagen and glycosaminoglycan. The collagen-glycosaminoglycan biodegradable matrix provides a scaffold for cellular invasion and capillary growth. INTEGRA™ Wound Matrix provides coverage over exposed bone, tendon, cartilage and joints.

The product may be used in combination with INTEGRA™ Bilayer Wound Matrix.

Benefits of INTEGRA™ Wound Matrix include:

• Provides immediate wound coverage

• Highly conformable for various anatomical sites
• Excellent performance in deep donor sites
• Can be used in combination with INTEGRA™ Bilayer Wound Matrix
• Room temperature storage
• Long shelf life
• Patients can begin rehabilitation with INTEGRA™ Wound Matrix in place
• Provides coverage over exposed bone, tendon, cartilage and joints. Of 166 instances of exposed internal structures that are ordinarily closed with flaps, Integra closed 90% of them ^[1]

[1] Gottlieb, Marc, M.D. and Jennifer Furman. Successful Management and Surgical Closure of Chronic and Pathological Wounds using Integra. Journal of Burns & Wounds, 2004, Volume 3, No. 2

Indications: INTEGRA™ Wound Matrix is indicated for the management of wounds including:
partial and full thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic
vascular ulcers, tunneled/undermined wounds, surgical wounds (donor sites/grafts, post-Moh's
surgery, post-laser surgery, podiatric, wound dehiscence), trauma wounds (abrasions, lacerations, second-degree burns, and skin tears) and draining wounds. This device is intended for one-time use.

INTEGRA™ Wound Matrix is available in the following sizes in both single and 5 pack configurations:

2 in x 2 in (25 sq cm)

• Wound Matrix IFU